A new article from the Bright Lab, titled “Multiparametric measurement of cerebral physiology using calibrated fMRI“, has been accepted for publication in NeuroImage.
In the context of a calibrated fMRI experiment, we simultaneously characterize BOLD, blood flow, blood volume, tissue oxygen extraction, oxidative metabolism, and vascular reactivity throughout the brain. Rather than focus on a single aspect of brain physiology, considering the relationships of multiple physiological parameters allows more accurate and precise characterization of neurovascular health in a range of clinical applications. This paper is part of a special issue on Physiological MRI, in collaboration with Paula Croal, Nic Blockley, and Dan Bulte at the University of Oxford.