Research details coming soon



Advanced Methods for Cleaning up fMRI Time-Series

Educational course from the Organization for Human Brain Mapping annual meeting, 2017, Vancouver.

Organizers: Molly Bright and Kevin Murphy; Faculty: Cesar Caballero Gaudes, Daniel Handwerker, Jonathan Power, Molly Bright, Ludovica Griffanti, Prantik Kundu







BOLD Signal Physiology

Educational presentation at the ISMRM annual meeting, 2017, Honolulu.








In Press

Bright MG, Whittaker JR, Driver ID, Murphy K (2020) Vascular physiology drives functional brain networks. Neuroimage.

Moia S, Stickland RC, Ayyagari A, Termenon M, Caballero-Gaudes C, Bright MG (2020) Voxelwise Optimization of Hemodynamic Lags to Improve Regional CVR Estimates in Breath-Hold FMRI. Conf Proc IEEE Eng Med Biol Soc 2020.

Published Articles

Whittaker JR, Driver ID, Venzi M, Bright MG, Murphy K (2019) Cerebral autoregulation evidenced by synchronized low frequency oscillations in blood pressure and resting-state fMRI. Frontiers in Neuroscience 13:433.

Dury RJ, Falah Y, Gowland PA, Evangelou N, Bright MG, Francis ST (2019) Ultra-high-field Arterial Spin Labeling MRI for non-contrast assessment of cortical lesion perfusion in Multiple Sclerosis. Eur. Radiol. 29(4):2027-2033.

Bright MG, Croal PL, Blockley NP, Bulte DP (2019) Multiparametric measurement of cerebral physiology using calibrated fMRI. Neuroimage 187:128-144.

Whittaker JR, Bright MG, Driver ID, Babic A, Murphy K (2019) Changes in cerebral arterial blood volume during lower body negative pressure measured with MRI. Neuroimage 187:166-175.

Bright MG, Tench CR, Murphy K (2017) Potential pitfalls in denoising resting state fMRI data using General Linear Models. Neuroimage 154:159-168.

Driver ID, Whittaker JR, Bright MG, Muthukumaraswamy, S, Murphy K (2016) Arterial CO2 fluctuations modulate neuronal rhythmicity; implications for MEG and fMRI studies of resting state. J Neurosci 36(33):8541-50.

Tewarie P, Bright MG, Hillebrand A, Robson SE, Gascoyne LE, Morris PG, Meier J, Van Mieghem P, Brookes MJ (2016) Predicting haemodynamic networks using electrophysiology: the role of non-linear and cross-frequency interactions. NeuroImage 230:273-292.

Bright MG, Murphy K (2015) Is fMRI “noise” really noise? Resting state nuisance regressors remove variance with network structure. Neuroimage 114:158-169.

Whittaker J, Driver I, Bright MG, Murphy K (2015) The absolute CBF response to activation is preserved during elevated perfusion: implications for neurovascular coupling measures. Neuroimage 125:198-207.

Bright MG, Bianciardi M, de Zwart JA, Murphy K, Duyn JH (2014) Early anti-correlated BOLD signal changes of physiologic origin. Neuroimage 87:287-296.

Bright MG, Murphy K (2013) Reliable quantification of BOLD fMRI cerebrovascular reactivity despite poor breath-hold performance. Neuroimage 83:559-568.

Bright MG, Murphy K (2013) Removing motion and physiological artifacts from intrinsic BOLD fluctuations using short echo data. Neuroimage 64(1):526-537.

Bulte DP, Kelly M, Germuska M, Xie J, Chappell MA, Okell TW, Bright MG, Jezzard P (2012) Quantitative measurement of cerebral physiology using respiratory-calibrated MRI. Neuroimage 60:582–591.

Bright MG, Donahue MJ, Duyn JH, Jezzard P, Bulte DP (2011) The effect of basal vasodilation on hypercapnic and hypocapnic reactivity measured using magnetic resonance imaging. J Cereb Blood Flow Metab 31(2):426-38.

Bright MG, Bulte DP, Jezzard P, Duyn J (2009) Characterization of regional heterogeneity in cerebrovascular reactivity dynamics using novel hypocapnia task and BOLD fMRI. Neuroimage 48(1):166-75.

Editorials, Comments, and Book Chapters

Bright MG, Murphy K (2017) Cleaning up the fMRI time series: mitigating noise with advanced acquisition and correction strategies. Neuroimage 154:1-3.

Bulte DP, Bright MG, Howe F, Corfield D (2016) Vascular Response to Hypoxia and Hypercapnia. In: Bammer R ed. MR & CT Perfusion Imaging: Clinical Applications and Theoretical Principles.  Wolters Kluwer. ISBN/ISSN: 9781451147155.